Skin infections can appear suddenly and look alarmingly similar, which can make identifying them at home quite tricky. Two common culprits are impetigo and cold sores. Both are contagious and typically affect the area around the mouth, but they have different causes, treatments, and implications.
In this blog, we’ll break down the key differences between impetigo and cold sores—what they are, how they spread, and when to seek help. If you’re dealing with either, our Pharmacy First service at Market Harborough Pharmacy is here to support you.
What Is Impetigo?
Impetigo is a highly contagious bacterial skin infection. It most commonly affects young children, though adults can get it too. The condition usually begins as red sores or blisters, typically around the nose or mouth, which then burst and form a yellowish crust.
The two main types of impetigo are:
- — Non-bullous impetigo – the most common type, causing sores that burst quickly and leave a golden crust.
- — Bullous impetigo – causes larger fluid-filled blisters, often affecting areas like the trunk.
It’s usually caused by Staphylococcus aureus or Streptococcus bacteria and spreads through skin-to-skin contact or by touching contaminated objects.
What Is a Cold Sore?
A cold sore, or fever blister, is a small blister that typically appears on or around the lips. It’s caused by the herpes simplex virus (usually HSV-1). Unlike impetigo, which is bacterial, cold sores are viral and tend to recur over time.
Once you’ve been infected with HSV-1, the virus stays in your body and can reactivate when triggered by stress, illness, sun exposure, or hormonal changes. Cold sores usually start with a tingling or burning sensation, followed by blistering and crusting.
Key Differences Between Impetigo and Cold Sores
Although impetigo and cold sores can look similar at first glance, there are a few clear differences between the two:
Cause: Impetigo is a bacterial infection caused by Staphylococcus or Streptococcus bacteria. Cold sores, on the other hand, are caused by the herpes simplex virus (usually HSV-1).
Appearance: Impetigo usually starts as red sores or blisters that burst and develop a yellowish crust. Cold sores begin with a tingling sensation before forming small fluid-filled blisters that eventually scab over.
Location: Both infections commonly affect the area around the mouth, but impetigo can also appear on the nose and other parts of the face or body. Cold sores almost always develop on or around the lips.
Understanding these differences can help you spot which condition you’re dealing with—but if you’re not sure, it’s always best to speak to a healthcare professional.
How Are They Treated?
Impetigo treatment
Impetigo treatment often involves prescription antibiotic creams or oral antibiotics, especially for more widespread cases.
Cold sore treatment
Cold sores don’t require antibiotics. Antiviral creams or tablets (like aciclovir) can reduce the severity and duration if used early. Many cold sore treatments are available over the counter, and we’re happy to advise on what might work best.
Preventing Spread
Both conditions are infectious, so prevention is important—especially if you’re around children, the elderly, or anyone with a weakened immune system.
To reduce the risk of spreading impetigo:
- — Avoid touching the sores or crusts
- — Keep the area clean and covered
- — Don’t share towels, bedding, or utensils
- — Stay off school or work until 48 hours after starting antibiotics or until sores have healed
To reduce cold sore transmission:
- — Avoid kissing or close contact during an outbreak
- — Don’t share lip balms, cutlery, or drinks
- — Wash hands regularly, especially after touching the affected area
- — Avoid oral sex while a sore is present to prevent genital herpes transmission
When to Seek Professional Advice
Whether you suspect impetigo or a cold sore, it’s important to get a professional opinion—especially if:
- — The sore is spreading or not improving
- — You experience fever, pain, or swelling
- — It’s your first time experiencing symptoms
At Market Harborough Pharmacy, we provide a fast, accessible route to treatment for minor skin conditions through our Pharmacy First service. This means you may not need to see your GP—we can handle it all for you in-pharmacy.
Why Choose Pharmacy First for Impetigo?
Pharmacy First allows qualified pharmacists to assess and treat common conditions like impetigo without the need for a doctor’s appointment. It’s convenient, fast, and available to eligible NHS patients at no cost.
Here’s why it’s a great option:
- — Get treatment without waiting for a GP
- — Professional diagnosis and prescription options
- — Support and advice from trusted local healthcare providers
Don’t Guess—Get Support from Your Local Pharmacy
Still unsure whether you’re dealing with impetigo or a cold sore? Let us help you get a clearer picture and fast access to treatment.
At Market Harborough Pharmacy, we’re here to provide expert advice and care through services like Pharmacy First. Whether you need antibiotic treatment for impetigo or guidance on managing cold sore outbreaks, we’ve got you covered.
Book an appointment with our team or contact our pharmacy today—we’re here to help you feel better, faster.
This blog was written on behalf of Market Harborough Pharmacy by Pharmacy Mentor.
